In life, there are times when we want to give up. At these times, we question the value of our goals. Are they worth it? Will achieving them make me happy? Any worthy endeavour comes littered with obstacles - some insurmountable, others trivial. To recognise the difference is true wisdom.
When you can't have what you want, want something else. Want what you really want. Want what you need.
Take the way you need to take. Find your way, force your way, be the way.
It is a shame to fall short when you know you have not shown your best. Let failure not deter you. Let it guide you to your inevitable success.
One of the deepest human needs is to be understood. One of the simplest things to communicate is passion. Find your passion. Pursue it relentlessly. Be understood. Be happy.
update: see http://thescenicroute0.wordpress.com/2011/12/10/passion-makes-all-things-alive-and-significant/